产品货号：
Z11645
中文名称：
BARD1抗体
英文名称：
Anti-BARD1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BARD1 Antibody |
| 指标别名 | BARD 1;BARD1;BRCA1 associated RING domain 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | BARD1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human BARD1 recombinant protein (Position:P709-A758). |
| 实际分子量 | 87KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene.This gene encodes a protein which interacts with the N-terminal region of BRCA1.In addition to its ability to bind BRCA1 in vivo and in vitro,it shares homology with the 2 most conserved regions of BRCA1:the N-terminal RING motif and the C-terminal BRCT domain.The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth,including the products of tumor suppressor genes and dominant protooncogenes.This protein also contains 3 tandem ankyrin repeats.The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1,implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression.This protein may be the target of oncogenic mutations in breast or ovarian cancer.Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q99728 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | BRCA1 associated RING domain 1 |
| 蛋白名全称 | BRCA1-associated RING domain protein 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
相关搜索：BARD1抗体，BARD1多抗，Anti-BARD1 Antibody